Overview
Decapeptide-12 is a synthetic peptide ingredient designed to interrupt the melanin production process at the source. Instead of just covering up dark spots, it works inside the skin to slow down how much pigment your cells actually produce.
Technical Specifications
|
Parameter |
Specification |
|
INCI Name |
Decapeptide-12 |
|
CAS Number |
Available Upon Request |
|
Molecular Formula |
C65H90N18O17 |
|
Molecular Weight |
1395.50 Da |
|
Appearance |
White to Off-White Lyophilized Powder |
|
Assay (HPLC) |
≥98.0% |
|
Peptide Content |
≥95.0% |
|
Purity Grade |
Cosmetic Grade |
|
Solubility |
Soluble in Water |
|
Recommended Use Level |
0.5%–2.0% |
|
Optimal Formulation pH |
5.0–7.0 |
|
Heavy Metals |
≤10 ppm |
|
Loss on Drying |
≤8.0% |
|
Storage Condition |
2–8°C, Dry and Protected from Light |
|
Shelf Life |
24 Months |
|
Analytical Methods |
HPLC, Mass Spectrometry (MS) |
|
Origin |
Synthetic Peptide |
Key Feature
Targeted Mechanism: Competitively inhibits tyrosinase activity to block early-stage melanin synthesis, minimizing the formulation cytotoxicity and skin-barrier risks typically associated with hydroquinone, AHAs, or retinoids.
Clinical Validation: Backed by in vitro binding affinity data and human clinical trials (Mexameter testing) demonstrating a statistically verifiable reduction in the Melanin Index (MI) within 28 days at a 2.0% use level.
Batch Consistency: Synthetic nature mitigates the seasonal composition drift, heavy metal fluctuations, and pesticide residue risks inherent in botanical extracts, preventing color and odor variations in commercial scale-up.
Formulation Synergy: Validated chemical compatibility with Niacinamide, Alpha-Arbutin, and Tranexamic Acid, guaranteeing zero antagonistic precipitation or chemical discoloration in multi-target brightening matrices.
OEM & Private Label Support
Customized Formulation Options: Decapeptide-12 can be incorporated into water-based serums, oil-in-water creams, hydrogels, and localized spot-correctors based on your product concept and market positioning, maintaining stable clearing efficiency within a pH range of 5.0–7.0.
Flexible Pilot Production: Small-scale production starts from 500–1,000 finished units, allowing brands to evaluate market performance before full-scale manufacturing.
Compatibility Packaging Selection: Available in airless pumps, amber dropper bottles, and aluminum-lined tubes to prevent photo-oxidation and preserve peptide bioactivity throughout its shelf life.
Technical & Regulatory Documentation: Every contract manufacturing run includes complete stability testing data, freeze-thaw compatibility reports, and localized COA/MSDS documentation for global customs clearance.
Quality Control
Regulatory Compliance: Produced in an ISO 9001 and cGMP-compliant facility with an annual capacity of 500 kg pure peptide powder, ensuring structural supply security for multinational contract manufacturers.
Lot Traceability & Validation: Every commercial lot undergoes mandatory HPLC and Mass Spectrometry (MS) analysis, cross-linking each shipped container directly to its original synthesis logs, raw material certificates, and validated laboratory COA.
Salt-Form Customization: In-house R&D provides custom counter-ion conversions (Acetate vs. HCl forms) and standardized liquid masterbatch dilutions to streamline direct dosing in large-scale commercial manufacturing.
Supply Chain Support
R&D Sampling: Complimentary 10g to 50g qualification samples available upon verified RFQ, accompanied by full batch retention COA and spectral documentation. Commercial trial MOQ starts at 100g, with standard contract tiers at 1 kg and 5 kg lots.
Industrial Packaging: Secured in high-barrier aluminum foil bags or fiber drums lined with double-sealed anti-static PE liners to prevent moisture ingress and oxidation.
Lead Times: Ex-stock items are ready for dispatch within 5–7 business days; custom scaling or bulk synthesis contracts require a 3–4 week production lead.
Storage & Logistics: Guaranteed 24 months shelf-life when stored sealed at 2–8°C; standard air freight shipping uses temperature-monitored packaging to safeguard peptide stability during transit.
FAQ
Q: Is Decapeptide-12 supplied as a cosmetic-grade or pharmaceutical-grade material?
A: Decapeptide-12 is generally supplied as a cosmetic raw material intended for topical skincare formulations. Additional quality documentation can be provided according to project requirements.
Q: Can the ingredient be supplied in customized concentrations?
A: Yes. Besides pure peptide powder, customized liquid concentrates and pre-diluted solutions can be developed for easier manufacturing and dosing.
Q: What is the typical batch size for commercial production?
A: Commercial manufacturing programs commonly range from 1 kg to 20 kg per batch, with larger production schedules available under long-term supply agreements.
Q: Does Decapeptide-12 require cold-chain transportation?
A: For most destinations, insulated packaging is sufficient. Temperature-controlled shipping options are available for regions with extended transit times or extreme climates.
Q: Are retain samples kept after production?
A: Yes. Retention samples are archived for future quality investigations, customer audits, and batch verification purposes.
Hot Tags: decapeptide-12, China decapeptide-12 manufacturers, suppliers, factory, price, buy, cream formulation ferulic acid use, cream oil phase active tetrahexyldecyl ascorbate, ferulic acid formulation stability, kojic acid inci, mild vitamin c derivative for sensitive skin, skin tone evening ingredient alpha arbutin







