Kojic Acid Dipalmitate (KAD)

Kojic Acid Dipalmitate (KAD)
Details:
Kojic Acid Dipalmitate, often called KAD, is a lipid-modified version of Kojic Acid created by attaching it to two palmitic acid molecules. It helps reduce melanin formation by inhibiting tyrosinase, a key enzyme in the skin pigmentation process.
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Description
Technical Parameters

Introduction

 

Kojic Acid Dipalmitate, often called KAD, is a lipid-modified version of Kojic Acid created by attaching it to two palmitic acid molecules. It helps reduce melanin formation by inhibiting tyrosinase, a key enzyme in the skin pigmentation process.

 

Product Specification

 

Item

Specification

CAS No.

79725-98-7

Molecular Formula

C38H68O8

Molecular Weight

652.94 g/mol

Appearance

White to Off-White Crystalline Powder

Purity (HPLC)

≥98.0%

Melting Point

68–72°C

Solubility

Oil Soluble

Heavy Metals

≤10 ppm

Microbial Limits

Complies with Cosmetic Raw Material Standards

Shelf Life

24 Months

Storage Condition

Store in a Cool, Dry Place Away from Direct Sunlight

 

Key Benefits

 

High-Efficiency Tyrosinase Inhibition: Lipophilic whitening agent tailored for stable, leave-on anti-spot emulsions, offering direct melanogenesis suppression without cellular toxicity.

 

Thermal & Photolytic Resilience: Exhibiting a superior molecular structure that resists degradation caused by heat and UV radiation, overcoming the inherent rapid browning vulnerability of free Kojic Acid.

 

Discoloration Mitigation: Validated via 12-week accelerated stability tracking at 40°C to guarantee no batch yellowing, safeguarding product aesthetic consistency throughout a 24-month retail shelf life.

 

PH-Independent Poly-Phenol Stability: Eliminates the classic pH-dependent oxidation and subsequent graying/browning traps typical of traditional phenolic antioxidant and whitening systems.

 

Quality Assurance

 

Chromatographic Purity Control: Batch-by-batch HPLC analysis securing a minimum chemical purity of 99.0%, with free kojic acid residues strictly capped under 0.1% to eliminate formula incompatibility.

 

Supply Chain Matching: Every commercial shipment features a laboratory COA cross-referenced and hard-stamped to match the physical drum lot numbers displayed on the cargo packing list.

 

Retained Sample Archival: Standard 100g verification samples from each operational batch are securely archived for 24 months to facilitate immediate, traceable retrospective testing.

 

Independent Third-Party Audits: Optional external inspection validation (via SGS or Intertek protocols) executed upon corporate procurement mandate with a fixed 5–7 business day execution timeline.

 

OOS Segregation Protocol: Rigorous non-blending mandate enforcing immediate chemical quarantine and structured CAPA (Corrective and Preventive Action) logging for any out-of-specification batch.

 

Commercial Terms

 

Initial accounts operate on a 30% advance deposit / 70% balance payment terms before port dispatch; Net-30 commercial credit lines are unlocked following three consecutive trouble-free transaction cycles.

 

Complimentary 100g analytical samples prepared and dispatched within 3–5 business days, routed via international courier on a freight-collect basis.

 

MOQ: Strategic 25 kg minimum order quantity for commercial pilot trials; standard repeat contract allocations are scheduled based on a 1 Metric Ton threshold, with custom labeling unlocked at 500 kg.

 

Logistics & Packaging

 

Standard Incoterms: FOB Shanghai or FOB Ningbo ports; scalable EXW, CIF, and full DDP delivery frameworks available for strategic North American and European manufacturing locations.

 

Inventory Availability: 7–10 business days processing for standard ex-stock warehouse volumes; 20–25 days lead time for custom mechanical particle size micronization or bespoke packaging requests.

 

Packaging Configurations: Shipped in 25 kg UN-approved fiber drums outfitted with secure double LDPE internal liners (yielding 8–10 MT per 20ft FCL). R&D pilots and small-batch scales are supported via 1 kg aluminum foil pouches or 5 kg mini-drums.

 

Compliance & Certifications

 

European Union Status: Fully compliant with EU Cosmetic Regulation (EC) No 1223/2009, operating independently of the strict 1.0% restriction cap enforced on free Kojic Acid.

 

United States Status: Evaluated as safe for topical skincare applications under current US FDA cosmetic ingredient compliance structures.

 

China Market Access: Listed within the Inventory of Existing Cosmetic Ingredients in China (IECIC) and fully approved for cross-border CSAR safety assessment filings.

 

Technical Audit Pack: Every production lot is backed by a batch-specific HPLC-COA, GHS-compliant SDS, full REACH Registration Number documentation, Allergen-Free Declaration, and certified Heavy Metal/Microbiological assays.

 

FAQ

 

Q: What information is typically required before requesting a quotation?

A: To receive an accurate quotation, buyers are encouraged to provide estimated annual volume, target market, packaging requirements, delivery destination, and intended application type.

Q: What is the recommended usage level in cosmetic formulations?

A: Typical use levels range from 1% to 5%, depending on the desired brightening effect, formulation design, and local regulatory requirements.

Q: What is the expected shelf life of finished products containing KAD?

A: Shelf life depends on the complete formulation and packaging system. Under normal storage conditions, KAD is commonly used in cosmetic products designed for 24-month commercial shelf life targets.

Q: Can you support custom specifications for formulation development?

A: Yes. Depending on order volume and technical requirements, customized specifications such as purity range, particle size distribution, and packaging format can be developed to support specific formulation and manufacturing processes. Our technical team works directly with customers during product evaluation and scale-up stages to ensure compatibility with production requirements.

Q: Can you provide customized packaging for private label or OEM projects?

A: Yes. Customized packaging options are available for OEM and private label programs, including custom labels, outer cartons, drum markings, and barcode identification. Packaging specifications can be adjusted based on project volume, destination market requirements, and warehouse handling preferences.

 

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