Ascorbyl Tetraisopalmitate Vitamin C

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Ascorbyl Tetraisopalmitate (VC-IP) is a fat-soluble derivative synthesized by esterification of ascorbic acid (vitamin C) and isopalmitic acid. Its molecular formula is C₇₀H₈₀O₁₀ and its CAS number is 183476-82-6. The compound is a colorless to light yellow oily liquid with good skin permeability and stability. Its fat-soluble characteristics give it a high affinity in the skin barrier and enable it to penetrate deep into the skin. After absorption by the skin, Ascorbyl Tetraisopalmitate can be converted into an active form of ascorbic acid to exert an antioxidant effect. It has high stability and is not easily affected by light, oxygen and heat, making it suitable for a variety of formulation systems. This ingredient is often used in skin care products as a stable source of vitamin C.

Lipid-soluble structure improves skin penetration efficiency
Ascorbyl Tetraisopalmitate Vitamin C is the product of esterification of vitamin C molecules with four isopalmitic acid groups. Its structure significantly improves its lipid solubility, making it have a higher diffusion efficiency in the skin's oil layer. Compared with water-soluble L-ascorbic acid, VCIP can more easily penetrate the stratum corneum and reach the dermis, thereby releasing active vitamin C to participate in antioxidant reactions, collagen synthesis and melanin metabolism. Its skin penetration rate is about 3 times higher than that of water-soluble vitamin C. It can achieve a good active release effect at a concentration of 1% to 3%. It does not rely on pH adjustment or formulation auxiliary support. It has good dispersibility in creams, essences and oil products, and is often widely used by various cosmetics manufacturers in oil phases or composite systems. According to the physical and chemical indicators, its density at 20°C is 0.942 g/cm³, and its refractive index at 25°C is 1.462, presenting a transparent liquid state. This shows that the product can be evenly distributed in the formula and is not easy to precipitate, which is conducive to improving the uniformity and sensory stability of the finished product and reducing the cost of subsequent process adjustments.

High chemical stability ensures the maintenance of product activity
VCIP wraps the vitamin C main chain through ester bonds, greatly improving its resistance to heat, light and oxygen, avoiding the problem of rapid oxidation and deterioration of traditional vitamin C during product storage and use. Its chemical stability data shows that after 30 days of storage at 40°C, the activity retention rate is still more than 90%, and there is no rapid color change or precipitation under ultraviolet irradiation. This feature ensures that it can exist in the formula for a long time without affecting the stability of other ingredients. The product is a colorless to light yellow transparent liquid in appearance, with a color index of APHA 10, which is far below the standard limit of 100, further proving that its oxidation products are very few, and can meet the requirements of high-end skin care products for the appearance and transparency of raw materials. Due to its good stability, the product can achieve a shelf life of more than 12 months without adding antioxidants or multiple packaging conditions, effectively reducing the burden of packaging design and warehouse management. High stability also means that problems such as pH fluctuations and sensory changes caused by vitamin C degradation can be reduced, improving the safety of the product in the circulation link.

Multifunctional synergy to achieve dual effects of whitening and anti-aging
Ascorbyl Tetraisopalmitate Vitamin C can be slowly hydrolyzed into free L-ascorbic acid by esterase in the skin after percutaneous penetration. The latter is a key active substance in the skin's antioxidant and whitening mechanism. Its antioxidant function is manifested in its ability to neutralize active oxygen such as hydroxyl free radicals and superoxide anions, which can protect cell membranes and cell nuclei from oxidative damage, while stimulating the synthesis of type I and type III collagen, improving the structural strength and elasticity of the skin, and inhibiting UV-induced MMP activity, thereby slowing down wrinkle formation and skin sagging. Its whitening function mainly intervenes in the tyrosinase activity chain, reduces melanin production, inhibits melanosome transport, and dilutes the pigmented areas that have been generated, while also having the ability to repair photodamage. Continuous use of 3% concentration formula for 4 weeks can improve skin brightness by about 10%, reduce the area of ​​pigmentation by 8%~12%, and improve skin smoothness by more than 12% on average. Due to its comprehensive efficacy, VCIP is suitable for multi-functional positioning products, especially in high value-added skin care products such as sunscreen repair, whitening essence, and high-efficiency cream.

ZHENYIBIO-Focus On Cosmetics Ingredients

For thirteen years,ZHENYIBIO has been focusing on Whitening ingredient. As a professional manufacturer of Ascorbyl Tetraisopalmitate Vitamin C, we continuously improve production processes and strengthen cooperative services.

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(86)-0153 0920 6328

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alexxue@zhenyibio.com

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